Ring case detection yielded four secondary cases in only one community, possibly due to vector-borne transmission in this community, apparently absent in the others. Testing houses with infected-vectors was least expensive. There was no significant difference in prevalence across the screening strategies however a self-assessment of disease risk may have biased participation, inflating prevalence among residents of houses where no infestation was detected. No multivariate model with these variables fit the data better than a simple model including only the time lived in an area with triatomine bugs. Significant risk factors on univariate logistic regression for infection were age (OR 1.02 p = 0.041), time lived in a rural location (OR 1.04 p = 0.022), and time lived in an infested area (OR 1.04 p = 0.008). Cases had lived more time on average in rural places than non-cases (7.20 years versus 3.31 years, respectively). Infection was detected in 21 of 923 (2.28%) participants.
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